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SRX1881057: GSM2218835: SMAD2/3, MCF10A MII, TGFβ 1.5h_ChIP; Homo sapiens; ChIP-Seq
1 ILLUMINA (Illumina Genome Analyzer IIx) run: 27M spots, 972.3M bases, 385.7Mb downloads

Submitted by: NCBI (GEO)
Study: SMAD2/3 binding pattern in a breast epithelial cell line, MCF10A MII [ChIP-seq]
show Abstracthide Abstract
We report that SMAD2/3 are redirected to novel binding sites on the genome after prolonged TGFß stimulation. Overall design: SMAD2/3 ChIP-seq analyses were performed in MCF10A MII cells at 2 different time points after TGFß treatment.
Sample: SMAD2/3, MCF10A MII, TGFβ 1.5h_ChIP
SAMN05296861 • SRS1527768 • All experiments • All runs
Organism: Homo sapiens
Library:
Instrument: Illumina Genome Analyzer IIx
Strategy: ChIP-Seq
Source: GENOMIC
Selection: ChIP
Layout: SINGLE
Construction protocol: Chromatin isolation, sonication and immunoprecipitation using anti-SMAD2/3 antibody (#610843, BD Transduction Laboratories) were performed essentially as described (Isogaya et al., 2014; Morikawa et al., 2016). The library was prepared using NEBNext ChIP-Seq Library Prep Reagent Set for Illumina (New England Biolabs) or KAPA DNA Library Preparation Kits for Illumina (KAPA Biosystems).
Experiment attributes:
GEO Accession: GSM2218835
Links:
Runs: 1 run, 27M spots, 972.3M bases, 385.7Mb
Run# of Spots# of BasesSizePublished
SRR372353027,009,476972.3M385.7Mb2017-11-22

ID:
2687766

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